About the Study
Psoriasis is a chronic (long-term) disease that affects about 7 million Americans – both males and females and the young and the old, although the late-20s is the average time in life that people first experience its symptoms. In its most typical form, called plaque psoriasis, itchy or sore plaques of thick red skin develop, commonly with silvery scales. These plaques can appear anywhere on the body, but the most common locations include the knees, elbows, scalp, legs, and buttocks. Psoriasis may also affect fingernails and the genitalia. Beyond plaque psoriasis, there are other types of psoriasis: guttate, pustular, inverse, and erythrodermic.
Skin is inflamed in psoriasis, due to an over-active immune system. Recently, researchers have discovered that people with more severe forms of psoriasis also have inflammation throughout the inside of the body. About a third of people with psoriasis also get psoriatic arthritis, a type of arthritis that causes joints and the tissues surrounding the joints to become inflamed and painful. Other internal diseases, notably heart attacks, strokes, diabetes, hypertension, and depression, are also associated with psoriasis. Doctors and researchers are trying to learn more about this new understanding of psoriasis, especially its association with heart disease.
Psoriasis is not contagious and you cannot catch it from other people. In many cases, there is a family history of psoriasis and researchers have identified genes linked to the disease. Flares, or times when the symptoms are worse, can be common and many people report stress, infection, cold weather and certain medications may trigger this worsening or flare. Moderate-to-severe psoriasis may significantly impact quality of life, as many studies have demonstrated.
Right now, dermatologists at Oregon Medical Research Center are accepting adults, ages 18-75, for a new clinical research study. The study is for a new investigational topical medication for mild-to-severe psoriasis.
If you are age 18-75, and have had mild-to-severe plaque-type psoriasis for at least six months, you may qualify for a new clinical research study. By joining the study you will receive:
- Evaluations of your psoriasis by our dermatologists
- Study-related care and study medication at no cost (you do not need insurance to participate, but you will need to attend up to 7 scheduled visits to our office during a four-month period)
- Compensation for time and travel to attend study visits
What is the purpose of a clinical study?
Clinical studies (also called clinical trials) are used to learn about the safety and the effectiveness of possible new medications. Although there are many types of clinical trials, all must conform to strict rules set by the U.S. Food and Drug Administration (FDA). These rules help protect the rights and the safety of those who volunteer to take part in clinical trials.
Will I have to pay for anything if I participate?
If you qualify and choose to participate, you will receive study-related care (such as study medications and visits to our office) at no cost to you. You will also be compensated for your time and travel to attend study visits.
How long does the study last?
If you join the study, your participation will last up to approximately four months and require up to 7 scheduled visits to our office near Washington Square, at the Greenburg Road exit, just off Highway 217. These visits are an important part of the study, as they allow your study doctor to closely monitor your progress. Additionally, participants who successfully complete the study may have an option to enroll in a longer-term extension of the study.
Does this study have a placebo?
Most clinical studies have a control group who do not receive active study medication during the study, or for a period of time during the study. This study has an inactive placebo (1 in 3 may receive the placebo), but at week 12 participants on placebo who have successfully completed the study may have the option to enroll in a longer-term extension and be transitioned to the study medication.
What if I join the study and decide I do not want to participate anymore?
As with all clinical studies, your participation is completely voluntary and you may choose to leave the study at any time.
I’m interested in hearing more. What is the next step?
To learn more about the study, give us a call at 503-245-1525, Monday through Thursday, during normal business hours, or Sign Up Today and we will give you a call to provide additional information.